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GLP-1 Weight-Loss Drugs Comparably Effective for Patients Across Age, Race, and Starting Weight

John Hopkins University: Bloomberg School / March 2, 2026

Popular GLP-1 receptor agonist drugs (GLP-1 RAs) for weight loss appear to be similarly effective among patients of different ages, races, and starting weight, with women benefiting somewhat more than men, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

The study examined 64 clinical trials involving semaglutide (Ozempic), dulaglutide (Trulicity), and other drugs in this class. The trials collectively included tens of thousands of patients. The analysis found that on average women who took GLP-1 RAs lost about 11% of their starting weight, compared to about 7% among men. By contrast, the analysis showed similar effectiveness of the agents based on individuals’ age (under 65 versus 65 and older), race, ethnicity, starting body